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PT-141
Reconstitution Solution
REPRODUCTIVE & LIBIDO
PT-141
PT-141 is a synthetic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH). It has been extensively studied for its ability to activate melanocortin receptors, which are involved in a variety of physiological processes, including sexual function and energy regulation. PT-141 is provided in lyophilized powder form for research purposes focusing on sexual health and other physiological effects.
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MOLECULAR FORMULA:
C50H68N14O10
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Product Usage: For Research Use Only – Not for Human or Veterinary Use
This product is not a drug, food, cosmetic, or dietary supplement and has not been evaluated by the FDA. It is strictly intended for in vitro research by qualified professionals. Any use in humans or animals is strictly prohibited and may violate federal, state, or local laws, including the Federal Food, Drug, and Cosmetic Act. No therapeutic or diagnostic application is implied or permitted. The purchaser assumes all responsibility for compliance with applicable regulations.
PTP-141 Research Peptide
PT-141 is a synthetic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH). It has been extensively studied for its ability to activate melanocortin receptors, which are involved in a variety of physiological processes, including sexual function and energy regulation. PT-141 is provided in lyophilized powder form for research purposes focusing on sexual health and other physiological effects.
Chemical Info
| CAS Number | 189691-06-3 | |
| PubChem CID | 9941379 | |
| Molecular Weight | 1025.18 g/mol | |
| Molecular Formula | C50H68N14O10 | |
| Synonyms | Bremelanotide, Sexual Dysfunction Research Peptide | |
| Purity | ≥ 99% HPLC | |
Storage
Store in lyophilized form at -20°C to maintain compound stability.
Store protected from direct light exposure to reduce degradation.
Keep totally dry and avoid moisture exposure prior to reconstitution.
Keep vial tightly sealed when not in use to preserve integrity.
Neurological Mechanism of Sexual Arousal
PT-141 is a primary focus for investigating the activation of melanocortin receptors in the hypothalamus. Research suggests that by acting as a non-selective agonist of these receptors, PT-141 can trigger a cascade of neurotransmitters that facilitate sexual desire and erectile function. Researchers utilize this model to monitor the central signaling pathways that govern arousal, providing a distinct contrast to peripheral treatments that focus solely on vascular tissue.
Metabolic Signaling and MC4R Engagement
In metabolic studies, PT-141 is utilized to observe the effects of MC4 receptor activation. This receptor is known to play a critical role in energy balance and sexual behavior. Researchers examine how PT-141 can influence systemic metabolic shifts while simultaneously activating reproductive signaling. This research is vital for understanding how specific peptide analogs can modulate diverse physiological systems through a single receptor class.
Comparative Studies with Melanotan analogs
Emerging research utilizes PT-141 to investigate the differentiation between pigmentary effects and behavioral effects within the melanocortin family. While closely related to Melanotan 2, PT-141 is studied for its relative lack of melanocortin 1 receptor activation, making it a specialized tool for focusing on behavioral outcomes without significant changes in skin pigmentation. This allows researchers to isolate specific physiological variables in complex animal models.